Posts in category: Uncategorized

Parkinson’s disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms. It is currently estimated that more than 10 million people in the world are living with Parkinson’s disease, the second most common neurodegenerative disorder after Alzheimer’s. That number is expected to swell up to 14 million by 2040 in what is being referred to as the Parkinson’s pandemic.

Young people who are in higher education in England face a small increased risk of depression and anxiety, compared to their peers who are not attending higher education, finds a new study led by UCL researchers.

A new wearables study tracking over 25,000 people provides the best evidence yet that short bouts of incidental activity, the kind we do as part of daily living, could reduce risk of heart attack, stroke and even premature death—but the length of activity and intensity matters.

For some families, the year after childbirth may not only mean loads of diapers but stacks of unpaid medical bills as well.

Researchers have developed a machine learning model that shows promising results in predicting the risk of critical bleeding in patients with immune thrombocytopenia (ITP).

Chronic hepatitis B virus (HBV) infection poses a significant threat to global public health, contributing to liver-related morbidity and mortality. The current diagnostic methods for HBV-related diseases, such as laboratory tests, ultrasounds, computed tomography (CT), and liver biopsies, often overlap and consume valuable medical resources. In response to this challenge, a team of researchers have developed an innovative and cost-effective method to diagnose and predict HBV-related diseases based on blood tests.

A special supplement to the Journal of Alzheimer’s Disease presents insights and new directions in both basic and clinical research into neurodegenerative diseases. Because by 2050, the number of people suffering from brain disorders is estimated to reach 155 million, now is the time to think innovatively to discover new pathways for future brain studies.

Research led by Peiyin Hung has dug deeper into the challenges surrounding maternity care access that the health services policy and management assistant professor has been unveiling through her recent research. Adding to her dozen-plus publications on the topic in the past few years, Hung’s most recent paper appeared in The Milbank Quarterly where the authors described the dual barriers of digital access and transportation facing socioeconomically disadvantaged communities.

A multisite, international phase 2 trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation in patients with fibrodysplasia ossificans progressiva (FOP).

A new study shows that delivery of gene therapy to correct the gene mutations that cause CLN2 disease, or Batten disease, directly into the cerebrospinal fluid (CSF) has potential therapeutic effects. The study, conducted in nonhuman primates, is published in the journal Human Gene Therapy.