Arf1 inhibitors promote the infiltration of cytotoxic T lymphocytes into tumors by affecting lipid metabolism

In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers. However, the absence of tumoral killer T cells and the complexity of tumor microenvironment can both affect the immunotherapeutic efficacy. Therefore, it is urgent to develop novel anti-tumor agents that can effectively promote effector T cell infiltration in tumors.

Commonly used muscle-building dietary supplements are under regulated in Canada, finds study

A new policy analysis, published in the journal Performance Enhancement & Health, highlights several gaps in current Canadian policy regulating muscle-building dietary supplements. Muscle-building dietary supplements, including whey protein, creatine monohydrate, and amino acids, are used based on purported benefits to muscular growth and recovery. These products are regulated by the Natural Health Products Regulations under Health Canada.