The first drug purporting to slow the advance of Alzheimer’s disease is likely to cost the U.S. health care system billions annually even as it remains out of reach for many of the lower-income seniors most likely to suffer from dementia.
Four ways to help kids overcome back-to-school anxiety
Heading back to school after a long summer break can be an exciting time for kids and caregivers. But for some students, the anxiousness of heading back to school may be fueled by fears or worry. In this Mayo Clinic Minute, Dr. Stephen Whiteside, a Mayo Clinic child psychologist, offers four tips on how to help kids overcome back-to-school anxiety.
Researchers identify lipid vascular ‘ZIP code’
Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular “ZIP code” in the lungs. Getting a drug to where it is needed in the human body is critical for successfully treating diseases including cancer and avoiding toxic side effects, but it remains a major challenge. One creative option has been to identify the unique protein receptors that are present on the surface of blood vessels at specific sites in the body that act like vascular ZIP codes. These ZIP codes can be physically paired with a ligand such as a small protein or antibody that can be harnessed to guide and deliver a package such as a drug or a diagnostic imaging agent to their specific molecular addresses. Some of these ligand-receptor pairs are already undergoing testing in clinical trials with anti-cancer and anti-obesity drugs.
More Americans than ever believe marijuana smoke is safer than cigarette smoke, but they’re wrong
As cannabis use has become legal in many U.S. states for medical or recreational use, Americans’ views on the drug may have gotten rosier.
A fate determination fork-in-the-road for germinal center Tfh and T memory cells
Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center (GC) responses during which high-affinity antibodies are generated.
Scientists identify genes linked to high production of key antibody
A collaboration led by UCLA and the Seattle Children’s Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.
Most people initiating opioid prescriptions have very low use trajectory
Most adults initiating treatment with prescription opioids have relatively low and time-limited exposure to opioids during a five-year period, according to a study published online Aug. 10 in JAMA Network Open.
In America’s prisons, suicide risk rises along with temperatures
Punishing heat is a fact of life inside America’s prisons without air conditioning, and it is taking a serious toll on prisoners’ mental health.
Medical writing: Caution warranted if using ChatGPT
When it comes to health care, it’s best to ask a professional. This oft-repeated adage also applies to scientists who might be tempted to use the ChatGPT artificial intelligence model for medical writing.
Why are Black adults at greater risk of death from heart disease? Study blames social factors
Black Americans are 54% more likely to die of cardiovascular disease than White Americans, despite a substantial overall reduction in cardiovascular disease mortality nationwide.