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Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature.

New research published today in JAMA Surgery shows that when frail patients are connected to resources, including conversations with a physician about possible outcomes and help preparing their body for surgery, they are less likely to die one year after surgery.

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. There is a need for early detection of individuals at risk of developing sequelae. According to a new study, poor muscle health may be a marker of risk for this.

POLICE in Chililabombwe have arrested Kasumbalesa Bola Bet branch manager, Harrison Kalombwe for allegedly stealing over K123, 000 from the online sports betting company.

Copperbelt Commissioner of Police,  Peacewell Mweemba said Mulonyeni Tembo,  35, a regional manager for Bola Bet Zambia,   reported on behalf of the company that K123,391 cash was allegedly been stolen by Kalombwe, 26, of house number 106 Mine township in Chililabombwe.

Mr Mweemba said on Sunday, February 19, 2023, after Kalombwe opened the Bola Bet outlet in Kasumbalesa, their Lusaka-based supervisor noticed some suspicious transactions when some clients started playing spin games.

He said When Mr Tembo reported for duty the following day, his supervisor instructed him to verify some suspicious transactions in Kasumbalesa before discovering a K123, 391 cash shortfall on the balance sheet.

‘’ The Regional Manager was instructed to come and verify some of the suspicious transactions. On Monday, February 20, 2023, when he reported for work, he discovered that there is a shortfall of K 123,391 cash money on the balance sheet. On the actual closing balance there was K 229,588 but cash at hand was K 106,197 making a shortfall of K123, 391. “The matter was reported at Chililabombwe Police Station where it was established that the branch manager used the money for playing the spin. Docket was opened and an arrest has been made,’’ Mr Mweemba said.

The growing number of Alzheimer’s disease (AD) cases, projected to reach 135 million by 2050, highlights the urgent need for effective therapeutics. Accumulated evidence points to an impairment of the metabolic mechanism in Alzheimer’s patients that develops several decades before the onset of dementia and deterioration of cognitive function. Reduced metabolism results from a dysfunction of the mitochondria, which is responsible for producing most of the energy in the cell but is also involved in cell death, inflammation and immune response.

A research team led by Dr. Tu Yiheng from the Institute of Psychology of the Chinese Academy of Sciences has found that people with chronic pain in multiple parts of the body had a higher risk of dementia and experienced broader and faster cognitive decline, including memory, executive function, learning, and attention.

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer’s disease-related genes, providing a potential mechanistic explanation for why Alzheimer’s is sometimes more frequent among adults who experienced obesity in midlife.

According to trends in male reproductive health data, sperm quality and testosterone levels have declined over the last few decades, sounding alarm bells for Michael Eisenberg, MD, a professor of urology at Stanford Medicine. It’s made him wonder: Should we be concerned about other differences in men’s reproductive health? Surmising that there may be more to uncover, Eisenberg set out to determine if physical anatomy has changed.

In a new study from Tel Aviv University published in the journal Nature Cancer, a team of researchers led by Prof. Neta Erez, head of the laboratory for the biology of tumors from the Department of Pathology at the Sackler Faculty of Medicine, identified and characterized a new mechanism that facilitates the formation of brain metastases and found that impairing this mechanism significantly reduced the development of brain metastases in mice.

People living in urban areas report significantly worse hay fever symptoms according to the first study to compare pollution levels with the severity and duration of real-time symptoms.