What really killed COVID-19 patients: It wasn’t a cytokine storm, suggests study

Secondary bacterial infection of the lung (pneumonia) was extremely common in patients with COVID-19, affecting almost half the patients who required support from mechanical ventilation. By applying machine learning to medical record data, scientists at Northwestern University Feinberg School of Medicine found that secondary bacterial pneumonia that does not resolve was a key driver of death in patients with COVID-19. It may even exceed death rates from the viral infection itself.

Older people have better mental well-being than 30 years ago, says study

Older people have better mental well-being than 30 years ago, according to a study conducted at the Gerontology Research Center at the Faculty of Sport and Health Sciences, University of Jyväskylä (Finland). The study, published in the Journal of Aging and Health, examined differences in depressive symptoms and life satisfaction between current 75- and 80-year-olds and the same-aged people who lived in the 1990s.

Scientists discover innate tumor suppression mechanism

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ago, researchers have so far been unsuccessful at determining exactly how it works. Now, in a recent study published in Cancer Discovery, researchers at The Wistar Institute have uncovered a key mechanism as to how p53 suppresses tumors.