Nearly 90% of patients with an aggressive subtype of non-Hodgkin lymphoma had their cancer go into remission in a small phase 2 clinical trial testing a treatment aimed at making chemotherapy more effective, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.
New online platform to support people with osteoporosis and their caregivers
The International Osteoporosis Foundation (IOF) has launched the Build Better Bones platform, a new online resource that provides people with osteoporosis, and their caregivers, with practical guidance on how to strengthen bones and reduce the risk of fragility fractures through targeted exercises and bone-healthy nutrition.
What really killed COVID-19 patients: It wasn’t a cytokine storm, suggests study
Secondary bacterial infection of the lung (pneumonia) was extremely common in patients with COVID-19, affecting almost half the patients who required support from mechanical ventilation. By applying machine learning to medical record data, scientists at Northwestern University Feinberg School of Medicine found that secondary bacterial pneumonia that does not resolve was a key driver of death in patients with COVID-19. It may even exceed death rates from the viral infection itself.
Kids with nonverbal autism may still understand much spoken language
About a third of children with autism aren’t able to speak—but that doesn’t mean they’re unable to listen and comprehend, a new study reports.
Report: US death rate declined in 2022, COVID deaths fell by almost half
Preliminary mortality data for 2022 finds America making its way back from the devastation of the pandemic, with a significant 5.3% decline in deaths compared to 2021. The data was published in the May 5 issue of the CDC journal Morbidity and Mortality Weekly Report.
FTD-TPI plus bevacizumab found to increase survival in refractory advanced CRC
Treatment with trifluridine-tipiracil (FTD-TPI) plus bevacizumab yields longer overall survival than FTD-TPI alone among patients with refractory metastatic colorectal cancer, according to a study published in the May 4 issue of the New England Journal of Medicine.
Epilepsy medicine during pregnancy associated with increased risk of psychiatric disorders in children
Some types of epilepsy medicine taken during pregnancy are associated with an increased risk of severe psychiatric disorders in children.
Older people have better mental well-being than 30 years ago, says study
Older people have better mental well-being than 30 years ago, according to a study conducted at the Gerontology Research Center at the Faculty of Sport and Health Sciences, University of Jyväskylä (Finland). The study, published in the Journal of Aging and Health, examined differences in depressive symptoms and life satisfaction between current 75- and 80-year-olds and the same-aged people who lived in the 1990s.
Team performs first-of-its-kind, in-utero procedure to fix deadly vascular malformation
In a first, a team from Brigham and Women’s Hospital and Boston Children’s Hospital successfully treated an aggressive vascular malformation in an infant’s brain before birth, avoiding potentially fatal symptoms after delivery.
Scientists discover innate tumor suppression mechanism
The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ago, researchers have so far been unsuccessful at determining exactly how it works. Now, in a recent study published in Cancer Discovery, researchers at The Wistar Institute have uncovered a key mechanism as to how p53 suppresses tumors.