A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms. The findings, published in Nature Microbiology, could lead to new strategies to treat COVID-19, which still infects thousands and kills hundreds in the U.S. every week.
National kidney cancer study shows promising results
UC Davis Comprehensive Cancer Center has taken part in testing the anti-cancer drug everolimus as part of a phase III clinical trial to see if it helped people with kidney cancer. Results from the clinical trial showed that many patients with kidney cancer remained alive many years after they underwent surgery to remove the cancer.
Giving patients anti-platelet medication sooner after stroke treatment may significantly improve patient recovery
Administering anti-platelet medication within 24 hours of mechanical thrombectomy, an effective procedure for stroke, may help patients more successfully recover and prevent high-risk individuals from experiencing additional strokes, according to a study presented today at the Society of NeuroInterventional Surgery’s (SNIS) 20th Annual Meeting.
New stroke surgery eligibility criteria may dramatically increase lifesaving stroke surgery rates
A recent study presented today at the Society of NeuroInterventional Surgery’s (SNIS) 20th Annual Meeting noted that U.S. rates of endovascular thrombectomy, a lifesaving stroke treatment, are projected to increase dramatically based on new criteria.
Filter tip stent retrievers may allow neurointerventionalists to remove blood clots on first try during stroke treatment
Research presented today at the Society of NeuroInterventional Surgery’s (SNIS) 20th Annual Meeting shows that different types of stent retriever tips may result in improved patient outcomes when performing mechanical thrombectomy to treat stroke.
NPTX2 protein may predict mild cognitive impairment years before symptoms, study suggests
Results of a long-term study of cognitively healthy adults—most with a family history of Alzheimer’s disease—have added to evidence that low spinal fluid levels of a protein linked to learning and memory in mice may serve as an early predictor of mild cognitive impairment (MCI) years before symptoms appear.
Study shows HEPA filters substantially improve air quality during bushfire season
Portable air purifiers fitted with high-efficiency particulate air (HEPA) filters can substantially improve indoor air quality during bushfire events, according to new research from CSIRO, Australia’s national science agency.
Cardiac reparative and immune regulatory role of hPSC-derived epicardial cells uncovered for infarcted hearts
Recently, research groups led by Prof. Yang Huangtian from Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS) and collaborator Prof. Gao Ling from Shanghai East Hospital of Tongji University found that intramyocardial injection of human embryonic stem cell-derived epicardial cells (hEPs) at the acute phase of myocardial infarction (MI) ameliorates functional worsening and scar formation in mouse and swine hearts.
High-salt diet in rats slows metabolism and energy production of kidneys
Some parts of the metabolic pathway (the process of turning food into energy) slow in response to a high-salt diet, even as the kidneys produce and use more energy when exposed to high salt intake. The surprising finding is documented in a new research study by first author Satoshi Shimada, Ph.D., in the journal Function. Shimada and other researchers from the Medical College of Wisconsin and Jackson Laboratory in Bar Harbor, Maine, noted this result is similar to what happens in malignant tumors.
Researchers report on a low-cost potential therapy for spinal cord injuries
A spinal cord injury is a life-altering event, and the effects, such as muscle weakness and paralysis, can dramatically disrupt a person’s life. While there is no cure for paralysis, there has been some progress in developing potential treatment options to improve symptoms. Still, much of it remains out of reach to many patients. A person with a complete spinal cord injury may benefit from a spinal cord stimulator, but cost, safety and patient willingness to undergo surgery are among the barriers to treatment.