A research team led by Sheri Holmen, Ph.D., investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.
In a study in the journal Diabetes Technology & Therapeutics (DTT), investigators evaluated biomarkers for cardiovascular disease (CVD) and diabetic kidney disease (DKD) in overweight and obese (OW/OB) adults with type 1 diabetes treated with tirzepatide, a dual-incretin approved for use in individuals with type 2 diabetes associated with CVD and DKD.
Microdosing, or low-dose treatment of psychedelics such as lysergic acid diethylamide (LSD), has gained popularity in recent years as a potential method for alleviating symptoms of attention-deficit/hyperactivity disorder (ADHD). However, the first-ever randomized clinical trial investigating the pharmacological effects of psychedelics found that microdosing LSD is as effective as a placebo in improving ADHD symptoms.
Using a novel quantitative chemoproteomic strategy, a research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University has uncovered a protective role of dopamine (DA) in regulating the function of the microtubule-associated protein Tau. This discovery deepens our understanding of dopamine’s physiological and pathological roles in the human brain.
Public bodies should collect distinct data on both sex and gender identity to ensure accuracy and clarity of nationally held data, concludes a UK Government-commissioned report led by a UCL academic.
Genetic information collected through research studies like Geisinger’s MyCode Community Health Initiative can provide important—and previously unknown—information to participants about their risk for disease.
Swirling inside every cell are millions of microscopic messages called messenger RNAs (mRNAs). The messages are the genetic blueprints for proteins, which determine the behavior and health of the cell.
Researchers at The University of Texas at El Paso have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide. The results of the study were recently published in the International Journal of Molecular Sciences.
As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease, among others.
A study from Hiroshima University found that when people were told to imagine their virtual bodies in pain, their brains resisted the illusion of ownership. Their findings could provide insights into why some people may struggle with feeling connected to their own bodies, particularly in contexts involving depersonalization or negative physical states.