Demystifying a genetic disease of the heart muscle

Affecting 1 in 500 people, hypertrophic cardiomyopathy is a condition in which the walls of the left ventricle, the heart’s main pumping chamber, become abnormally thick. “HCM is one of the primary causes of sudden death among young, apparently healthy patients; it is also a frequent cause of heart failure requiring surgery or a transplant,” says Dr. Rafik Tadros, a cardiologist and associate professor in Université de Montréal’s Faculty of Medicine.

Xylazine detected in US–Mexico border drug supply, study finds

Researchers at the University of California San Diego School of Medicine, in collaboration with the Prevencasa free clinic in Tijuana, Mexico, have confirmed the presence of xylazine in the illicit drug supply at the U.S.–Mexico border. While xylazine remains less common in the Western U.S., border cities serve as key trafficking hubs and may have higher rates of emerging substances.

Smartwatch data: Study finds early health differences in long COVID patients

People who later experienced persistent shortness of breath or fatigue after a SARS-CoV-2 infection were already taking significantly fewer steps per day and had a higher resting heart rate before contracting the virus, according to a study by the Complexity Science Hub (CSH) published in npj Digital Medicine. This may indicate lower fitness levels or pre-existing conditions as potential risk factors.