Possible association found between neutrophil migration into sensory ganglia and fibromyalgia pain

A team of biomedical researchers from Queen Mary University of London, Hebrew University and University College London has found evidence of an association between fibromyalgia-type symptoms and migration of neutrophils into sensory ganglia. In their study, reported in Proceedings of the National Academy of Sciences, the group explored possible causes of fibromyalgia in mouse experiments.

A rapid and inexpensive paper-based test for multiplexed sensing of biomarkers

Centralized laboratory testing has been a standard tool for diagnosing common illnesses. However, laboratory-based testing generally requires expensive medical equipment and involves complex operation protocols that can only be completed within a medical facility by well-trained personnel. These requirements elongate testing time and prevent the widespread use of diagnostics in remote and resource-limited regions due to limited access to centralized labs. To address some of these limitations, point-of-care (POC) sensors were developed as alternative diagnostics tools with simple and rapid operation, compact size, and low cost.

Molecular determinant favoring head and neck cancer development identified

In addition to their role in energy metabolism, mitochondria play important roles in other cellular processes, such as apoptosis, calcium signaling and the synthesis of certain biomolecules. Mitochondria have also been implicated in the development and progression of cancer. In some cases, cancer cells may overproduce certain mitochondrial proteins, known as oncoproteins, that contribute to the uncontrolled growth and survival of cancer cells.