Cart is empty During the peak of the COVID-19 pandemic, a constant public fear was the rise of a new variant of the disease. Among the SARS-CoV-2 viral mutations, some were alarming, such as omicron, delta, and gamma. The strains with greater virulence and ability to invade the immune system are defined as variants of concern, as they also have the potential to overwhelm the health system, increasing the number of admissions to intensive care units.
Emulation of randomized clinical trials with nonrandomized database analyses
The complete findings of the RCT-DUPLICATE demonstration project are published today in JAMA.
Almost half of people with concussion still show symptoms of brain injury six months later
Even mild concussion can cause long-lasting effects to the brain, according to researchers at the University of Cambridge. Using data from a Europe-wide study, the team has shown that for almost a half of all people who receive a knock to the head, there are changes in how regions of the brain communicate with each other, potentially causing long term symptoms such as fatigue and cognitive impairment.
Higher rates of HIV diagnoses found among mental health service users
New research has found HIV is 2.5 times more frequent in people who use mental health services than the general population in South London. The paper was published today in BMJ Open.
Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study
Mothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving birth to a premature or growth-restricted baby, finds a 10-year nationwide audit of hospital admissions records in the US and published online in the open access journal RMD Open.
Junk food ads trigger positive emotions, healthy foods not so much
You might not care about the fast-food commercial shots of juicy burgers or creamy milkshakes, but they might change your beliefs about these items, whereas shots of fresh salads and berries might not, according to a new study.
Researchers report on emerging treatment for children with long COVID and recurrent fever
Researchers at National Jewish Health have found that a subset of children suffering recurring fevers as a result of long COVID-19 have benefited from a daily medication treatment commonly used for gout and periodic fever syndrome. Using the drug colchicine, researchers saw rapid improvement not only in their fevers but also with other long COVID symptoms such as brain fog, fatigue, and achiness. The case study is published in The Journal of Allergy and Clinical Immunology: In Practice.
Even as SARS-CoV-2 mutates, some human antibodies fight back
An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2. In a new investigation, scientists from La Jolla Institute for Immunology (LJI) have shown how antibodies, collected from this clinical study volunteer, bind to the SARS-CoV-2 “Spike” protein to neutralize the virus.
Autistic children exhibit aggression more frequently, study shows
At least half of all autistic children experience some form of aggression, such as hitting, kicking or name-calling, while their parents are tasked with helping them cope and integrate socially. Yet the prevalence and characterization of aggressive behaviors across autistic development are poorly understood.
Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic
A new research paper was published in Aging, titled “Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.”