MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes. Deregulation of MYC proteins occurs in more than half of all cancers and is associated with poor patient prognosis and outcomes. Numerous researchers have devoted significant efforts to try to target MYC proteins as a therapeutic approach to treat cancer. However, this has been extremely challenging to date, and other complementary strategies are being investigated.
Many disabled Americans and single parents face hunger
Many Americans went hungry in 2021, including disproportionate numbers of people with disabilities and single parents, a new government report shows.
A more convenient and accessible way to diagnose Alzheimer’s disease?
Despite extensive research and encouraging findings, Alzheimer’s disease (AD) remains difficult to diagnose based on signs and symptoms alone. But what if one day, a blood sample during an annual check-up could be used to identify the disease?
Important role of intestinal immune cells in iron deficiency identified for the first time
Iron deficiency is one of the five main causes of impaired health. It affects 30 percent of the world’s population, particularly women. Why iron deficiency can occur, even if enough iron is supplied through the diet, has not yet been sufficiently clarified in scientific research.
Patient-rated tardive dyskinesia linked to QoL, social functioning
For antipsychotic-treated outpatients, patient-rated severity and impact of possible tardive dyskinesia (TD) is associated with health-related quality of life and social functioning, according to a study published online March 9 in the Journal of Patient-Reported Outcomes.
Hopelessness about the future is a key reason some Black young adults consider suicide, new study finds
Feeling hopeless about the future is one of the primary reasons Black young adults consider suicide. That is one of the key findings from a new study I published in the Journal of Racial and Ethnic Health Disparities. Hopelessness proved to be the most common reason that Black men considered suicide, and it was one of the most common reasons Black women consider suicide.
$700M LOST IN MINERAL TAX EVASION SYNDICATE
By OLIVER SAMBOKO
Some unnamed mining company has been evading paying tax to the tune of $700 million by understating its taxable income and tax liability, the latest Financial Intelligence Centre (FIC) Report has revealed.
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Child with psoriasis negatively impacts mom’s quality of life
A child with psoriasis can have a negative effect on the mother’s quality of life, according to a study published online March 31 in the Journal of Cosmetic Dermatology.
Brain diseases are better classified using analysis of gene activity, shows study
Research led by Yashar Zeighami at McGill University, Canada, provides a new way to characterize brain diseases. The study, published in the open access journal PLOS Biology on April 20 shows that comparing the transcriptomes (the map of activity for all genes in the genome) related to different brain diseases can help us understand the mechanisms underlying the diseases, and why certain ones are comorbid. The method can also find new relationships among diseases, which could have an impact on clinical treatment options.
A gene involved in Down syndrome puts the brakes on neurons’ activity in mice, new study shows
Researchers from the University of Michigan have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice.