Posts in category: Uncategorized

Inhibition of the PREP enzyme was successful in stopping the progression of frontotemporal dementia in a mouse model of the disease, according to a new study published in Science Translational Medicine. PREP inhibitor treatment also reduced the accumulation of tau protein in neurons, which is typical of dementias.

For patients undergoing cesarean delivery, prophylactic use of tranexamic acid does not lead to a lower risk for a composite of maternal death or blood transfusion, according to a study published in the April 13 issue of the New England Journal of Medicine.

Need a little spring—or buzz—in your step? A wearable electrical-stimulation and vibration-therapy system designed by Rice University engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time. Focusing on the T-cell instead, Penn State researchers have partnered with Evaxion Biotech on a study that is the first to demonstrate the effectiveness of an artificial intelligence-generated vaccine in a live viral challenge model. Such a vaccine may provide long-lasting immunity against future emerging variants and could be used as a model for other seasonal viral diseases like the flu.

Predictions are becoming more and more a part of our lives, and they are becoming increasingly useful in medical science as the science evolves. Increased understanding of disease and its treatments allows us to use predictions based on predictive biomarker signatures to optimize treatment outcomes for increasingly specific subject groups.

Parents’ perceptions of the COVID-19 vaccine long-term comparative risk and their responsibility for children getting sick if vaccinated are associated with lower vaccine uptake among children, according to a study published online April 13 in Pediatrics.

Postoperative follow-up using smartphone app-assisted monitoring for patients undergoing breast reconstruction and gynecologic oncology surgery is associated with improved quality of recovery, according to a study published online April 12 in JAMA Surgery.

The addition of metastasis-directed therapy (MDT), consisting of definitive radiation therapy to all sites of disease, to hormone therapy results in improved progression-free survival for men with oligometastatic prostate cancer, according to a study published online April 6 in JAMA Oncology.

It’s not new for young people to develop an interest in their favorite pop singer or actor, but it can be problematic if that adoration turns toxic.

Although the Inflation Reduction Act of 2022 (IRA) aimed to increase patient access to prescription drugs and decrease spending, researchers warn that it may have unintended negative impacts on patients in the long run.