Pregnant women whose household tap water had higher levels of lithium had a moderately higher risk of their offspring being diagnosed with autism spectrum disorder, according to a new study led by a UCLA Health researcher.
Combination therapy a promising option for advanced kidney cancer patients already treated with immunotherapy
Immunotherapies, such as anti-PD-1 and anti-PD-L1, have become standard first line therapies for patients with advanced renal cell carcinoma (kidney cancer). Most patients, however, eventually experience disease progression, with no consensus on what therapy to use next.
Community-based program helps moms in poorer countries improve babies’ brain health
A program of facilitated, community-based groups to teach women and their partners from pregnancy until the baby is one about nutrition, sensitive caregiving, play, first aid, health and avoiding family violence has been shown to improve the brains of these women’s children. The children have significantly better cognitive, language and motor development at the age of two than those whose mothers had usual health care.
To ice or not to ice? Icing can promote muscle regeneration after mild injury
Applying ice to a muscle injury is a widespread first-aid treatment, but exactly what effect does this have on the muscle regeneration and does it really help? Cumulative research by a multi-institutional Japanese research collaboration reveals that “to ice or not to ice” may depend on the degree of muscle injury.
Tayali in court for harassing Chief Mukuni online
ECONOMIC and Equity Party president Chilufya Tayali has been dragged to court for going online on Facebook where he accused Senior Chief Mukuni of Southern Province of being behind the country’s gassing incidents between 2019 and 2020. In November last year, Mr Tayali,48, was live on his Facebook page talking about governance issues among them […]
Predicting multi-omics from genotypes with OmicsPred
Work by an international research team led by Yu Xu and Michael Inouye at the Department of Public Health and Primary Care, University of Cambridge, has resulted in a unique resource for predicting multi-omics data directly from genotypes. The details of how the team developed the OmicsPred resource are in an article, “An atlas of genetic scores to predict multi-omic traits,” published in the journal Nature. A Research Briefing on the study is published in the same journal issue.
Tumor-infiltrating T cells may be markers to predict patients’ responses to cancer immunotherapy
New insights into a population of tumor-infiltrating T cells may ultimately allow doctors to predict how patients will respond to checkpoint blockade immunotherapy, a form of cancer treatment with advantages that doctors say could benefit a wider patient population.
Association of alleles with risk of relapse in ANCA-associated vasculitis in the Japanese population
Vasculitis is a group of conditions that results in inflammation of the blood vessels. Symptoms include rash, shortness of breath, vision loss, and kidney failure depending on the location of the inflamed vessels. A rare type of vasculitis, ANCA-associated vasculitis (AAV), is associated with the presence of antineutrophil cytoplasmic antibodies (ANCA); these antibodies are directed against components in the cytoplasm of neutrophils.
Study: Metformin and leucine prevent cellular senescence and proteostasis disruption
Aging coincides with the accumulation of senescent cells within skeletal muscle that produce inflammatory products, known as the senescence-associated secretory phenotype, but the relationship of senescent cells to muscle atrophy is unclear. Previously, researchers found that a metformin + leucine (MET+LEU) treatment had synergistic effects in aged mice to improve skeletal muscle structure and function during disuse atrophy.
Study finds one of every six autistic children are expelled from daycare
Daycare can be a brutal start for some of our society’s youngest and most vulnerable people.