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Patients who have multiple tumors in one breast may be able to avoid a mastectomy if the tumors can be removed while leaving enough breast tissue, according to research led by the Alliance in Clinical Trials in Oncology and Mayo Clinic Comprehensive Cancer Center. Patients would receive breast-conserving therapy: a lumpectomy followed by whole-breast radiation therapy, rather than mastectomy. The study is published in the Journal of Clinical Oncology.

Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional or incorrectly positioned neurons can lead to severe neuropathological consequences. Mutations in genes coordinating this program are often linked to neurodevelopmental disorders; however, environmental stressors such as nutrient scarcity or malnutrition can also influence the development of the brain. Still, very little is known about the importance of specific nutrients and the role of metabolism during brain development.

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they’ve escaped from a primary tumor.

Physicians currently use assessments like heart chamber size and systolic function to diagnose and monitor cardiomyopathy and other related heart conditions. A paper published in the journal Med on March 29 suggests that another measurement—cardiac sphericity, or roundness of the heart—may one day be a useful implement to add to the diagnostic toolkit.

While serfs toiled and knights jousted in Europe and samurai and shoguns rose to power in Japan, the medieval peoples of the Swahili civilization on the coast of East Africa lived in multicultural, coral-stone towns and engaged in trade networks spanning the Indian Ocean.

Researchers have found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

“Go outside and play” is the time-tested strategy for generations of parents and caregivers ready to see their little ones tuckered out by exercise. But the strategy may be losing some of its impact as more children face more hot days, according to new research from The University of Texas at Austin. A team found that, as the weather gets hotter, preschool-aged children become more sedentary.

  Join us NOW as we bring you an exclusive live-stream of the ???????????????????????? ???????????? ???????????????????????????????????? ???????????????? in the Republic of Zambia.???????? Be a part of this momentous event as global leaders, activists, and academics come together to discuss pressing issues, share innovative ideas, and build a stronger democratic future for all. ???????? ???? ????????????????????’???? […]

 POLICE  have arrested two suspected criminals in connection with the gruesome murder of the 10-year-old girl identified as Universal Kamushi of Lusaka West who was went missing on March 24, 2023. The suspects have been identified as Harrison Chisenga aged 25 of Chipata Compound and Jacob Phiri aged 36 of Ngombe Compound. And Police have […]

By LUCY PHIRI
AN arresting officer has told the Lusaka Magistrate Court that Raphael Nakacinda did not defame President Hakainde Hichilema when he claimed that the head of State had met judges.
Detective Chief Inspector Innocent Makukwani has testified that it was not defamatory to say the President was meeting judges.
Detective Chief Inspector Makukwani was responding to a question by defence Lawyer Mr. Jonas Zimba during cross examination.

Mr. Zimba had asked if it was defamatory if one says the President was meeting judges.
In this matter, Patriotic Front (PF) Information and Publicity Secretary, Raphael Nakacinda aged 43 of farm number 1794, Kafue denied defaming President Hakainde Hichilema contrary to section 69 of the penal code chapter 87 of the laws of Zambia.
Meanwhile, the court has set April 19, 2023 as a date it will rule on whether or not Nakacinda has a case to answer or not after the state informed it that they had closed its prosecution case.
Mr. Mukukwani submitted before the court that he made up his mind to arrest and charge Nakacinda with the offence of defamation of the President because he saw him uttering the remarks on a television footage that he obtained from Muvi television.
He testified that he saw and heard Nakacinda defaming President Hakainde Hichilema after viewing a footage that he obtained from Muvi television.
“I based my arrest on the remarks that Nakacinda issued which were offensive against the President. I did not get a satisfactory response from him in the warn and caution statement i recorded from him because the he opted to remain silent,” he said.
Mr. Makukwani submitted that on December 18, 2021 he reported for duty around 7: 30 hours and in the afternoon he was assigned to investigate a case of defamation of the President.
He said it was alleged in the matter that Nakacinda had made remarks at the High Court grounds in Lusaka after addressing a group of people among them journalists that Mr Hichilema had begun summoning judges in the night at his residence to intimidate and coerce them to help him form a one-party state Government. Mr Makukwani alleged that the statement was broadcast by several media among them Muvi Television.
“Acting on the matter, I obtained the footage of Nakacinda’s address from Muvi Television and after going through it, it was discovered that he uttered the said words. I extended my interrogations to State House where i met with the private principal secretary to the president, Alfred Chipoya who is in charge of making appointments for the President and gave me the President diary for that week,” he said.
Mr Makukwani further said that he was given the President’s diary and after checking, he established that the President had not met anyone from the judiciary (judges) in the month of December.
He submitted that many other people complained about Nakacinda’s remarks among them Ackson Mabeta, Moses Mulonda and Eric Munabembe of which he interviewed them on the matter.
“I summoned Nakacinda to the police station and was brought by his lawyers, I warned and cautioned him about the charge of defamation but he denied. I then proceeded to charge him with the offence of defamation of the President because i heard him uttering the statements in a footage he obtained from Muvi,” he said.
Further in cross examination, when asked by Mr. Francis Daka whether he interviewed Mr Hichilema on the issue to find out if he had complained about Nakacinda’s remarks, he responded in the negative.
It is alleged that Nakacinda on December 13, 2021 in Lusaka, with intent to bring the name of Mr Hichilema into hatred, ridicule and contempt, did cause to be published defamatory matter by word of mouth, where he addressed people at the High Court of Zambia, which was also broadcasted by Muvi television that “ His Excellency
President Mr Hakainde Hichilema had begun to summon Judges at his private residence, intimidating and coercing them to frustrate PF legal battles.”