Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

Why do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop the blood cancer? In a new study published in Blood, scientists from the USC Stem Cell laboratory of Rong Lu discovered a mechanism that linked a leukemic mutation to varying potentials for disease development—a discovery which could eventually lead to a way to identify patients with the mutation who are most at risk.

Study: Good physical fitness does not protect children from obesity-related low-grade inflammation

The increased prevalence of childhood obesity has resulted in an increased incidence of sustained low-grade inflammation since childhood. Obesity is the key factor in increasing low-grade inflammation. However, high levels of physical fitness are thought to protect against obesity-induced health impairments. A study by the University of Jyväskylä and the University of Eastern Finland found that even good physical fitness itself does not reduce low-grade inflammation in children.

A device developed by researchers can improve cancer surgery—clinical trials initiated

First-in-human clinical trials have been initiated at Kuopio University Hospital with a device that assists in the identification of cancerous tissue during surgery. The tissue monitoring technique developed by startup company Marginum is based on the interdisciplinary research of the University of Eastern Finland, Kuopio University Hospital Neurosurgery and the Eastern Finland Microsurgery Center.

Q and A: Travel safety tips

I have a group of friends with whom I love to travel. We plan several trips a year, and this spring we are planning to go outside the U.S. and visit the Caribbean. We will stay at an all-inclusive resort in a popular destination and do a few sightseeing day trips in the area. Are there things we should do to be safe while traveling?