Immune system cells in the gut linked to stress-induced depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression. Targeting changes mediated by these immune cells in the gut, with drugs or other therapies, could potentially bring about new ways to treat depression.

Patients found to overwhelmingly prefer immediate access to test results, even when the news may not be good

In April 2021, new federal rules went into effect mandating that health care providers make nearly all test results and clinical notes immediately available to patients. Evidence suggests that patients may gain important clinical benefits by reviewing their medical records, and access through electronic patient portals has been advocated as a strategy for empowering patients to manage their health care and for strengthening patient-clinician relationships. However, concerns remain about the effects of releasing test results to patients before clinicians offer counsel or interpretation.

Stigma-coping intervention empowers people with HIV and drug use to engage in health, substance use care

Stigma negatively impacts the health of people with human immunodeficiency virus (HIV) and those with HIV who inject drugs experience stigma on multiple levels. Stigma leads to impaired utilization and retention in addiction treatment, less access to harm reduction services and reduces HIV care success. Unfortunately, there is a lack of interventions specifically targeting stigma related to HIV and substance use among people with HIV who inject drugs.

Spectroscopy probe could enhance deep brain stimulation procedure for Parkinson’s

Deep brain stimulation (DBS) has become an increasingly common treatment for patients with advanced Parkinson’s disease, but the procedure still carries significant risks. A new probe that performs two types of spectroscopy could make the procedure safer and improve success rates by helping doctors more accurately navigate instruments inside the brain. The research team identified white and gray matter using principal component analysis (PCA), proving that spectroscopic measurements could be suitable for neuronavigation.