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B lymphocytes—also known simply as B cells—play a central role in the immune system. If pathogens enter the body, B cells are activated and develop into plasma cells, which then release antibodies. One important step in this process is the germinal center reaction. If the B cells’ maturation into plasma cells is disrupted, multiple myeloma can develop—one of the most common blood cancers. This disease has a variety of subtypes and is not yet curable.

An experimental COVID-19 vaccine produced with technology based on a decades-old method, elicited virus-neutralizing antibodies in higher proportion than the amount induced by mRNA immunizations, a Phase 1 clinical trial has found.

Northwestern Medicine scientists have uncovered a mechanism by which exercise activates metabolic benefits in the body, according to a new study published in Cell Metabolism.

Cancer patients might one day benefit from being administered immune cells from healthy donors. But as things stand, receiving donor cells can cause severe or even fatal immune reactions. A researcher at ETH Zurich has now developed a technology that avoids these.

A higher-calorie nutrition plan isn’t more distressing for hospitalized teens and young adults with anorexia than a lower-calorie plan, a new study led by UC San Francisco researchers found.

A new texting intervention that University of British Columbia researchers helped develop is more effective at promoting healthy sexual decision-making and reducing pregnancies among sexual minority teens than most existing interventions in the U.S.

For many people, social interactions can be a source of dread. While some of us revel in parties, meetings and lunches, others are planning their exit strategy before they even step into a room.

While research has long established disparities in health outcomes among individuals living with sickle cell disease (SCD), few studies have quantified these gaps. A new study published in Blood Advances finds that the average life expectancy of publicly insured patients living with SCD is roughly 52.6 years. In contrast, the CDC reports that the average life expectancy in the United States is 73.5 years for men and 79.3 years for women, demonstrating the considerable burden SCD can have on affected populations.

Childhood obesity rates continue to rise in the United States, putting kids at risk for asthma, sleep apnea, type 2 diabetes, and other health conditions. Children prenatally exposed to both tobacco and cannabis had a 12 times higher risk for obesity by middle childhood (9–12 years of age) compared to non-exposed children, according to recent research, although more research is needed to determine if other factors account for these findings.

When caught early, lung cancer can often be successfully treated. The problem, however, is that there typically aren’t any symptoms in its early stages. That makes the early detection of lung cancer all the more important.