Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis. A relative, Yersinia pseudotuberculosis, causes gastrointestinal illness and is less deadly, but naturally infects both mice and humans, making it a useful model for studying its interactions with the immune system.
Normalizing tumor blood vessels may improve immunotherapy against brain cancer
A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma—the deadliest type of primary brain cancer—and other solid tumors.
Scientists reveal how XBP1s interacts with IL-15 to enhance the survival of natural killer cells
A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.
Autistic adolescents more likely to leave Medicaid as they enter adulthood in states without Medicaid waivers: Study
Many autistic people rely on important healthcare coverage from Medicaid for continued services and supports throughout their life. But when entering adulthood, autistic adolescents are facing increased risk of disenrollment from the Medicaid program if they live in a state without a Medicaid waiver. Recently published in JAMA Network Open, researchers from the A.J. Drexel Autism Institute at Drexel University examined whether state-level waivers were associated with reduced risk of Medicaid disenrollment among autistic transition-age youth.
Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells
A new review paper titled “Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells” has been published in Oncotarget.
How to help your child deal with separation anxiety
For some children, it can be hard when mom or dad leave them at daycare, school or even just with the other parent.
Parents, plan now for allergy-free summer camp
Planning for a safe summer camp experience requires some extra steps if your child has asthma or allergies.
Pediatric review takes stock of history and current status of long-acting growth hormone therapy
In 1957, Maurice Raben successfully isolated and purified the growth hormone (GH) from the pituitary gland, opening up a potential avenue of GH therapies. Children who were born with a deficiency of this hormone could now receive medical intervention in the form of daily injections to substitute the product into their body, thus avoiding the ill-effects of GH deficiency.
Promoting safer sleeping for babies in England could reduce rates of sudden infant death
Change is needed to the way safer sleep information is communicated, if risks to babies from unsafe sleeping practices are to be reduced, according to a new report involving UCL researchers.
China flu outbreak intensifies as infection rises for sixth week
An influenza outbreak in China picked up intensity over the past week as a major city prepared to enforce pandemic-style lockdowns to curb the surge in infections.