Q&A: No, that new study doesn’t show that masks are useless

Earlier this year, a review of research on masks by the Cochrane Library prompted headlines declaring that community masking has little impact on the spread of COVID-19. We asked Prof. Jason Abaluck, who co-authored a landmark randomized trial of mask promotion in Bangladesh, what conclusions we can draw from the review—and what the evidence says about the effectiveness of masks.

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

Scientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherapy CAR-T cells in patients with B cell lymphomas. Individualized microbiome information retrieved from patients’ gut microbiomes prior to initiation of CAR T therapy could accurately predict their subsequent responsiveness to therapy, but only in the condition that these patients were not pre-treated with broad spectrum antibiotics.