How IL-33 plays a key role in enabling the marathon runners of the immune system

When it comes to chronic infections and cancer, a particular type of immune cell plays a central role in our defenses. Researchers at the University of Basel have uncovered the key to the tenacity of these immune cells in coping with the marathon that is fighting a chronic infection. Their results lay the foundations for more effective therapies and vaccination strategies.

Deep-learning-based anatomical landmark identification in CT scans

Millions of people around the world undergo some type of orthodontic treatment each year due largely to developmental deformities in the jaw, skull, or face. Computed tomography (CT) imaging is the go-to technique for surgeons when planning such treatments, especially surgeries. This is because CT provides 3D images of the bones and teeth, which helps the surgeon analyze complex cases in detail and determine the best treatment procedure based on that.

Can certain nutrients protect against the effects of fetal alcohol exposure?

Fetal alcohol exposure at any stage of pregnancy can lead to congenital malformations, as well as cognitive, behavioral, and emotional impairments in offspring. New research conducted in mice and published in The FASEB Journal indicates that even very early embryos exposed to alcohol can experience growth restriction, brain abnormalities, and skeletal delays, but feeding pregnant mothers certain nutrients prior to conception and throughout pregnancy can reduce the incidence and severity of the alcohol-induced defects.

Bempedoic acid improves outcomes in statin-intolerant patients

The cholesterol-lowering drug bempedoic acid reduced the combined rate of major adverse cardiovascular events by 13%, meeting its primary endpoint in a large study of patients with high cholesterol who were unable to tolerate statins, according to research being presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology.

Trouble falling asleep at bedtime or in the middle of the night? It could impact your risk for developing dementia

Adding to the growing body of evidence on sleep disturbances and cognitive impairment, new research finds significant links between three measures of sleep disturbance and the risk for developing dementia over a 10-year period. The results, reported in the American Journal of Preventive Medicine, associate sleep-initiation insomnia (trouble falling asleep within 30 minutes) and sleep medication use with higher risk for developing dementia.