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Scientists working in the School of Biochemistry and Immunology in the Trinity Biomedical Sciences Institute at Trinity College Dublin have made an important breakthrough in understanding what goes wrong in our bodies during the progression of inflammatory diseases and—in doing so—unearthed a potential new therapeutic target.

Do cesarean-born babies miss out on essential microbes? New evidence suggests that the answer may be “no.” Researchers report on March 8 in the journal Cell Host & Microbe that mothers are able to transfer microbes to their babies via alternative, compensatory routes. While cesarean-born babies do receive less of their mother’s gut microbiome during birth, they make up for this by drinking their mother’s microbes in breastmilk.

Chronic kidney disease (CKD) is an independent risk factor for heart diseases, such as heart attacks, strokes or heart failure. A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Medical Center (BMC) analyzed this relationship in greater detail by examining kidney tissue collected during clinically indicated biopsies. In a paper published in JAMA Cardiology, the team reports associations between different types of kidney lesions, markers of CKD progression, and heart disease based on 597 adults without any history of heart disease from the Boston Kidney Biopsy Cohort.

 PremierCredit has launched the Wina Jila na PremierCredit campaign where anyone who invests a minimum of K100 will stand a chance to win a brand-new Toyota Hilux as the grand prize. The second prize is K50,000 per winner for five participants, including monthly wins of household appliances worth K10,000 and weekly prizes of K1, 500 […]

For the first time, researchers examine the effects of gender-affirming androgen therapy on breast tissue in transgender men with single-cell resolution. Their results give an unprecedented look into the changes that occur as a result of gender-affirming androgen therapy—a common and highly effective form of transgender care—but also have implications for the treatment of breast cancer across all populations. Notably, they show that gene expression in breast cells is silenced, and male gene programs are activated. This work appears in the journal Cell Genomics on March 8.

For the first time, a research team has identified and analyzed the steps by which immune cells “see” and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others.

It is one of the most challenging and critical issues in cardiovascular disease (CVD) treatment—how best to direct health resources to identify and treat those people at risk of a heart attack or stroke who don’t have CVD symptoms or traditional risk factors?

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), co-led by Professor Daniel G. Tenen and Associate Professor Polly Chen Leilei, made an unprecedented discovery of a hitherto unappreciated mechanism leading to ADAR2 (adenosine deaminases acting on RNA) dysregulation in core binding factor acute myelogenous leukemias (CBF-AML), and highlighted the functional relevance of the role of ADAR2 role in leukemogenesis. The research was published in the journal Blood on Feb. 16, 2023.

A study by researchers at The Ohio State University reveals new insights into the cause of certain cardiac arrhythmia disorders. The findings may lead to new treatments.

Curious about your mental well-being without seeing a psychiatrist? Or are you curious about how you can get a sense of your psychological well-being through social media? In reality, psychological well-being is difficult to assess in real time on a large scale. However, the popularity and proliferation of social media make it possible to sense and monitor the psychological well-being of online users in a nonintrusive way.