More children and adolescents are identifying as transgender and offered medical treatment, especially in the US. But some providers and European authorities are urging caution because of a lack of strong evidence.
Characterizing the harmful effects of immune cells in hypertension
Hypertension, or high blood pressure, tops the list of chronic health conditions. It affects about one-third of the world’s population, including nearly 44 percent of German citizens. If the pressure in the blood vessels is too high, the body’s organs—mainly the brain, the heart, and the blood vessels—suffer as a result.
Study: The risk of pregnancy complications for women with arthritis of the spine has decreased over time
Women with rheumatic diseases are at greater risk of complications during pregnancy and childbirth, but for women with arthritis of the spine, so called axial spondyloarthritis, the risks have decreased over the last ten years, according to a register study from Karolinska Institutet. This decrease coincided with an increased use of biologic drugs during the same period. The study was published in The Lancet Rheumatology.
Study examines decades-long suffering from obstetric injuries
Bowel leakage, the need for anal incontinence protection and a restricted social life may cause severe, decades-long suffering among women with obstetric injuries to the anal opening, according to a study from the University of Gothenburg.
The benefits of olive oil for health and well-being
Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer’s disease and to lower cholesterol.
New study is the first to examine contextual factors associated with higher rates of suicide in the Americas
A CAMH-led study of national suicide rates in 33 countries in the Americas over the past 20 years has found several key contextual factors associated with national rates of suicide.
Researchers discover biomarkers that could predict future allergic conditions
Researchers at National Jewish Health have identified an immune and lipid profile on the surface of the skin of infants that can predict the development of atopic dermatitis, or eczema, months before the onset of clinical illness. Atopic dermatitis affects 20-30% of children worldwide. Atopic dermatitis commonly occurs in children and can progress into what is called the atopic or allergic march, which refers to the progression of diseases that often begin early in life. Once the skin rash occurs, food allergies, asthma, and other problems can develop.
Psyllium fiber protects against colitis by activating bile acid sensor, researchers find
Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.
Susceptibility to pathogenic T cells in chronic lung disease may have genetic basis
Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.
Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability
FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. Various exon breakpoints of FGFR3-TACC3 have been identified in cancers.