Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature.
Patients identified as frail before surgery less likely to die one year after
New research published today in JAMA Surgery shows that when frail patients are connected to resources, including conversations with a physician about possible outcomes and help preparing their body for surgery, they are less likely to die one year after surgery.
UPND in Lungu-phobia – Kalaba
By NATION REPORTER
FORMER president Edgar Lungu seems to have become such a threat to the UPND that they have developed such a profane phobia that they wish they could have him completely confined and gagged from commenting on any national matter, Harry Kalaba has said.
And Raphael Nakacinda says former President Lungu has been uniquely magnanimous to allow President Hakainde Hichilema and the UPND to govern without any form interference by keeping away from politics and the maladministration that have become characteristic under them.
Mr Kalaba, the president of Citizen’s First Party says it is surprising that each time former President Lungu appeared in public, the UPND were politically convulsing and quivering with knee-jerk reactions.
Mr Kalaba said the behaviour by the UPND attacking former President Lungu for only asking the price of mealie meal and rice was uncalled for and an act of inadequacy on the part of the governing party.
Last week, the UPND attempted to gag Mr Lungu by banning his from making public appearances, claiming that the former head of State was throwing political innuendoes at his successor, President Hichilema.
On Monday, the UPND secretary general, Batuke Imenda claimed former President Lungu was shadow-boxing with President Hichilema and should therefore come out and declare himself politically active.
But Mr Kalaba said he did not see anything wrong with Mr Lungu making public appearances and commenting on national matters such as the prices of commodities like mealie meal.
“The UPND should leave President Lungu alone to enjoy his retirement. Former President Lungu is a Zambian, a citizen with all the rights. Who told the UPND that when you retire from politics, then you lose your rights to comment on national matters? It seems the UPND are so scared about former President Lungu because of their monumental failure to gover…otherwise they would not be suffering from Lungu-phobia. Let them accept that when one retires, it does not mean he cannot give an opinion on the governance of the country,” Mr Kalaba said.
Mr Kalaba advised that the UPND leadership should stop the vengeance, hatred, retribution and vindictiveness and concentrate on delivering on the promises they had made to Zambians.
He said former President Lungu did not commit any crime by asking how much mealie meal was costing and wondered why the UPND leadership was seeing innuendoes in such an innocent inquiry.
“The former President is not under house arrest. He is not in Lamara where Yasser Arafat was under house arrest. Let the UPND leave Mr Lungu alone to enjoy his retirement,” Mr Kalaba said.
And Mr Nakacinda said the phobia that the UPND were exhibiting each time former President Lungu appeared in public was worrying because the former head of State was not under house arrest.
Mr Nakacinda advised UPND secretary general Batuke Imenda to censure himself when issuing statements about the former president because they are not on the same level.
“A mature politician should be able to gauge the level of the person they are talking to and the issues they are labeling against him,” he said.
He said Mr Lungu was at liberty to engage the members of the public especially that he runs a foundation and various organizations go to him for wisdom on how society should be governed.
Mr Nakacinda said the UPND should be at peace because the only defense they have for now was to fulfil the promises they made to the people of Zambia.
Adverse muscle composition associated with increased mortality risk in people with fatty liver disease
Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. There is a need for early detection of individuals at risk of developing sequelae. According to a new study, poor muscle health may be a marker of risk for this.
Kasumbalesa Bola Bet manager nabbed for over K123, 000 theft
POLICE in Chililabombwe have arrested Kasumbalesa Bola Bet branch manager, Harrison Kalombwe for allegedly stealing over K123, 000 from the online sports betting company.
Copperbelt Commissioner of Police, Peacewell Mweemba said Mulonyeni Tembo, 35, a regional manager for Bola Bet Zambia, reported on behalf of the company that K123,391 cash was allegedly been stolen by Kalombwe, 26, of house number 106 Mine township in Chililabombwe.
Mr Mweemba said on Sunday, February 19, 2023, after Kalombwe opened the Bola Bet outlet in Kasumbalesa, their Lusaka-based supervisor noticed some suspicious transactions when some clients started playing spin games.
He said When Mr Tembo reported for duty the following day, his supervisor instructed him to verify some suspicious transactions in Kasumbalesa before discovering a K123, 391 cash shortfall on the balance sheet.
‘’ The Regional Manager was instructed to come and verify some of the suspicious transactions. On Monday, February 20, 2023, when he reported for work, he discovered that there is a shortfall of K 123,391 cash money on the balance sheet. On the actual closing balance there was K 229,588 but cash at hand was K 106,197 making a shortfall of K123, 391. “The matter was reported at Chililabombwe Police Station where it was established that the branch manager used the money for playing the spin. Docket was opened and an arrest has been made,’’ Mr Mweemba said.
New approach for treating Alzheimer’s shows success in mouse models
The growing number of Alzheimer’s disease (AD) cases, projected to reach 135 million by 2050, highlights the urgent need for effective therapeutics. Accumulated evidence points to an impairment of the metabolic mechanism in Alzheimer’s patients that develops several decades before the onset of dementia and deterioration of cognitive function. Reduced metabolism results from a dysfunction of the mitochondria, which is responsible for producing most of the energy in the cell but is also involved in cell death, inflammation and immune response.
More pain, more burdens: Researchers find link between chronic pain and dementia
A research team led by Dr. Tu Yiheng from the Institute of Psychology of the Chinese Academy of Sciences has found that people with chronic pain in multiple parts of the body had a higher risk of dementia and experienced broader and faster cognitive decline, including memory, executive function, learning, and attention.
Scientists tie obesity to Alzheimer’s-related genes
In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer’s disease-related genes, providing a potential mechanistic explanation for why Alzheimer’s is sometimes more frequent among adults who experienced obesity in midlife.
Is an increase in penile length cause for concern?
According to trends in male reproductive health data, sperm quality and testosterone levels have declined over the last few decades, sounding alarm bells for Michael Eisenberg, MD, a professor of urology at Stanford Medicine. It’s made him wonder: Should we be concerned about other differences in men’s reproductive health? Surmising that there may be more to uncover, Eisenberg set out to determine if physical anatomy has changed.
Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation
In a new study from Tel Aviv University published in the journal Nature Cancer, a team of researchers led by Prof. Neta Erez, head of the laboratory for the biology of tumors from the Department of Pathology at the Sackler Faculty of Medicine, identified and characterized a new mechanism that facilitates the formation of brain metastases and found that impairing this mechanism significantly reduced the development of brain metastases in mice.