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Advanced prostate cancer is cancer that has spread beyond the prostate to distant parts of the body. It is also called metastatic or stage 4 prostate cancer. While most advanced prostate cancer is incurable, treatments can slow or shrink the cancer, reduce symptoms and extend a person’s life.

Everyone knows the health risks of carrying too much fat around the waist and hips, but UVA Health scientists are developing a noninvasive way to assess the health risks of unseen fat around the heart.

The human immune deficiency virus (HIV) first entered public consciousness in the early 1980s, after cases of unfamiliar and deadly illnesses began to overwhelm medical centers across North America.

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination. How the brain and this highly diverse group of “switchboard operator” cells are connected is poorly understood.

The standard medication levodopa does not always work against tremors in Parkinson’s disease, especially in stressful situations. Propranolol, however, does work during stress, providing insight into the role of the stress system in tremors. MRI scans reveal that propranolol directly inhibits activity in the brain circuit that controls tremors. Doctors may consider this medication when levodopa is ineffective.

Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from the destruction of healthy cells.

Whenever a sink overflows, the flooding is usually caused by a blockage that has built up in the drains. Similarly, as we age, our bodies are flooded by aging, or senescent cells, which have stopped dividing but, instead of dying, remain active and build up in body tissues. Recent studies have shown that getting rid of these cells might delay age-related diseases, reduce inflammation and extend lives. Despite the great potential, however, there is currently no drug that can target these cells directly and efficiently.

Traces of Legionella were discovered in three courthouses in Baltimore City, the latest in a series of downtown public facilities where the bacteria has been detected.

The holiday season can be a time of joy, celebration, and indulgence in delicious foods and meals. However, for many, it can also be an emotional and stressful period.

UiB researchers are behind a new discovery that tells us how associated neurodegenerative diseases might develop. At the center of this discovery stands a molecule called NAD, or nicotinamide adenine dinucleotide. The results have been published in Nature Metabolism.