Predicting the liver-tropism of AAV vectors based on pre-clinical liver models

A new study reports the findings of the functional evaluation of six AAV vectors in 12 preclinical models of the human liver. The study, which aimed to uncover which combination of models is the most relevant for the identification of an AAV capsid variant for safe and efficient gene therapy to primary human hepatocytes, is published in Human Gene Therapy.

Leave A Comment

Your email address will not be published. Required fields are marked *