Persistent inflammatory state found in half of pediatric sepsis deaths

About half of pediatric patients who died of sepsis over the past 20 years at Vanderbilt University Medical Center had evidence of an inflammatory state called PICS (persistent inflammation, immunosuppression and catabolism syndrome), according to a study reported in the journal Chest. Children with PICS were more likely to have undergone heart surgery and had a higher incidence of fungal infections.

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