First large US clinical trial of cytisinicline finds the smoking cessation medication effective and well tolerated

The first large-scale U.S. clinical trial of cytisinicline, led by a Massachusetts General Hospital (MGH) investigator, found the smoking cessation medication to be effective and well tolerated in adults who wished to break their nicotine dependence. In the Phase 3 study published in JAMA, researchers reported that cytisinicline could offer adults who smoke a potential new treatment option.