Optimizing tissue engineering in rotator cuff repair

Retear and failure to heal are significant post-operative complications in rotator cuff repair surgery despite the use of commercially available rotator cuff repair grafts. Advances in tissue engineering have demonstrated that mesenchymal stem cells (MSCs) and growth factors (GFs) enhance the regeneration of rotator cuff tendon-to-bone insertion in animal models, as described in an article published in the journal Tissue Engineering Part B: Reviews.